Scientists discuss in 'The global regulator CodY regulates toxin gene expression in Bacillus anthracis and is required for full virulence' new findings in life sciences. "In gram-positive bacteria, CodY is an important regulator of genes whose expression changes upon nutrient limitation and acts as a repressor of virulence gene expression in some pathogenic species. Here, we report the role of CodY in Bacillus anthracis, the etiologic agent of anthrax," scientists in France report (see also Life Sciences).
"Disruption of codY completely abolished virulence in a toxinogenic, noncapsulated strain, indicating that the activity of CodY is required for full virulence of B. …
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